L37I (p.Leu37Ile) variant of HLA-DPB1 (P04440)
L37I (p.Leu37Ile) in HLA-DPB1 (P04440) is a missense change. The available record places it in the context of in allele DPB1*01:01, allele DPB1*03:01, allele DPB1*05:02, allele DPB1*06:01, a. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
L37I (p.Leu37Ile) variant details
- p.Leu37Ile
- 1000Genomes rs1126504
- ESP rs1126504
- ExAC rs1126504
- TOPMed rs1126504
- in allele DPB1*01:01, allele DPB1*03:01, allele DPB1*05:02, allele DPB1*06:01, a
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.17
- CADD 12.00
- PolyPhen-2 0.02
- SIFT 0.05
- Population evidence available
- Structural context available