L37H (p.Leu37His) variant of HLA-DPB1 (P04440)
L37H (p.Leu37His) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
L37H (p.Leu37His) variant details
- p.Leu37His
- gnomAD 6-33080681-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.19
- CADD 24.70
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the Middle Eastern population (allele frequency 0.0016)
- Structural context available
- Literature evidence available