L15V (p.Leu15Val) variant of HLA-DPB1 (P04440)
L15V (p.Leu15Val) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
L15V (p.Leu15Val) variant details
- p.Leu15Val
- ExAC rs771074929
- TOPMed rs771074929
- gnomAD rs771074929
- Missense
- Variant Prioritization Score for Impact Estimate 0.13
- REVEL 0.04
- CADD 11.60
- PolyPhen-2 1.00
- SIFT 0.55
- Most common in the Finnish in Finland (FIN) population (allele frequency 0.00066)
- Structural context available