L15M (p.Leu15Met) variant of HLA-DPB1 (P04440)
L15M (p.Leu15Met) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.17 / 1. The record also includes population frequency data and structural context.
L15M (p.Leu15Met) variant details
- p.Leu15Met
- ExAC rs771074929
- TOPMed rs771074929
- gnomAD rs771074929
- Missense
- Variant Prioritization Score for Impact Estimate 0.174
- REVEL 0.07
- CADD 18.90
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Latino/Admixed American population (allele frequency 2.2e-05)
- Structural context available