G49R (p.Gly49Arg) variant of HLA-DPB1 (P04440)
G49R (p.Gly49Arg) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
G49R (p.Gly49Arg) variant details
- p.Gly49Arg
- TOPMed rs1762799257
- Missense
- Variant Prioritization Score for Impact Estimate 0.384
- REVEL 0.25
- CADD 22.70
- PolyPhen-2 0.47
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available