G40A (p.Gly40Ala) variant of HLA-DPB1 (P04440)
G40A (p.Gly40Ala) in HLA-DPB1 (P04440) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
G40A (p.Gly40Ala) variant details
- p.Gly40Ala
- gnomAD 6-33080689-GGA-G
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.156
- CADD 10.70
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available