F38L (p.Phe38Leu) variant of HLA-DPB1 (P04440)
F38L (p.Phe38Leu) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
F38L (p.Phe38Leu) variant details
- p.Phe38Leu
- TOPMed rs1762793706
- gnomAD rs1762793706
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.30
- CADD 11.60
- PolyPhen-2 0.00
- SIFT 0.44
- Most common in the HGDP:MANDENKA population (allele frequency 0.5)
- Structural context available