E55V (p.Glu55Val) variant of HLA-DPB1 (P04440)
E55V (p.Glu55Val) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data and structural context.
E55V (p.Glu55Val) variant details
- p.Glu55Val
- ExAC rs770346059
- TOPMed rs770346059
- gnomAD rs770346059
- Missense
- Variant Prioritization Score for Impact Estimate 0.285
- REVEL 0.25
- CADD 21.10
- PolyPhen-2 0.50
- SIFT 0.48
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available