E55Q (p.Glu55Gln) variant of HLA-DPB1 (P04440)
E55Q (p.Glu55Gln) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
E55Q (p.Glu55Gln) variant details
- p.Glu55Gln
- TOPMed rs934444166
- Missense
- Variant Prioritization Score for Impact Estimate 0.295
- REVEL 0.24
- CADD 16.40
- PolyPhen-2 0.66
- SIFT 0.42
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available