E43G (p.Glu43Gly) variant of HLA-DPB1 (P04440)
E43G (p.Glu43Gly) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.20 / 1. The record also includes population frequency data and structural context.
E43G (p.Glu43Gly) variant details
- p.Glu43Gly
- ExAC rs755441461
- gnomAD rs755441461
- Missense
- Variant Prioritization Score for Impact Estimate 0.202
- REVEL 0.09
- CADD 24.10
- PolyPhen-2 0.93
- SIFT 0.03
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available