E34Q (p.Glu34Gln) variant of HLA-DPB1 (P04440)
E34Q (p.Glu34Gln) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E34Q (p.Glu34Gln) variant details
- p.Glu34Gln
- ExAC rs779874572
- TOPMed rs779874572
- gnomAD rs779874572
- Missense
- Variant Prioritization Score for Impact Estimate 0.275
- REVEL 0.07
- CADD 25.60
- PolyPhen-2 0.00
- SIFT 0.32
- Most common in the Middle Eastern population (allele frequency 0.00017)
- Structural context available