E34G (p.Glu34Gly) variant of HLA-DPB1 (P04440)
E34G (p.Glu34Gly) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
E34G (p.Glu34Gly) variant details
- p.Glu34Gly
- gnomAD 6-33080672-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.371
- REVEL 0.12
- CADD 20.30
- PolyPhen-2 0.13
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available