C44R (p.Cys44Arg) variant of HLA-DPB1 (P04440)
C44R (p.Cys44Arg) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
C44R (p.Cys44Arg) variant details
- p.Cys44Arg
- TOPMed rs1424116907
- gnomAD rs1424116907
- Missense
- Variant Prioritization Score for Impact Estimate 0.267
- REVEL 0.21
- CADD 23.10
- PolyPhen-2 1.00
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available