A31S (p.Ala31Ser) variant of HLA-DPB1 (P04440)
A31S (p.Ala31Ser) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data, published literature, and structural context.
A31S (p.Ala31Ser) variant details
- p.Ala31Ser
- gnomAD 6-33076132-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.123
- REVEL 0.03
- CADD 20.30
- PolyPhen-2 0.12
- SIFT 0.73
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available