A31D (p.Ala31Asp) variant of HLA-DPB1 (P04440)
A31D (p.Ala31Asp) in HLA-DPB1 (P04440) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data, published literature, and structural context.
A31D (p.Ala31Asp) variant details
- p.Ala31Asp
- gnomAD 6-33076133-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.158
- REVEL 0.11
- CADD 10.60
- PolyPhen-2 0.01
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available