Y64C (p.Tyr64Cys) variant of HLA-DPA1 (P20036)
Y64C (p.Tyr64Cys) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
Y64C (p.Tyr64Cys) variant details
- p.Tyr64Cys
- ExAC rs745439716
- TOPMed rs745439716
- gnomAD rs745439716
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.10
- CADD 26.00
- PolyPhen-2 0.92
- SIFT 0.00
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available