T72N (p.Thr72Asn) variant of HLA-DPA1 (P20036)
T72N (p.Thr72Asn) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data and structural context.
T72N (p.Thr72Asn) variant details
- p.Thr72Asn
- TOPMed rs1231617620
- gnomAD rs1231617620
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.10
- CADD 24.40
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available