S19T (p.Ser19Thr) variant of HLA-DPA1 (P20036)
S19T (p.Ser19Thr) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.07 / 1. The record also includes population frequency data and structural context.
S19T (p.Ser19Thr) variant details
- p.Ser19Thr
- ExAC rs757947184
- gnomAD rs757947184
- Missense
- Variant Prioritization Score for Impact Estimate 0.0708
- REVEL 0.03
- MetaLR 0.00
- MetaSVM -0.88
- CADD 0.32
- PolyPhen-2 0.01
- SIFT 0.61
- Most common in the Non-Finnish European population (allele frequency 3.6e-06)
- Structural context available