R6K (p.Arg6Lys) variant of HLA-DPA1 (P20036)
R6K (p.Arg6Lys) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R6K (p.Arg6Lys) variant details
- p.Arg6Lys
- TOPMed rs1358222756
- gnomAD rs1358222756
- Missense
- Variant Prioritization Score for Impact Estimate 0.125
- REVEL 0.08
- MetaLR 0.00
- MetaSVM -0.93
- CADD 9.76
- PolyPhen-2 0.55
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available