R2C (p.Arg2Cys) variant of HLA-DPA1 (P20036)
R2C (p.Arg2Cys) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
R2C (p.Arg2Cys) variant details
- p.Arg2Cys
- ExAC rs766701235
- gnomAD rs766701235
- Missense
- Variant Prioritization Score for Impact Estimate 0.133
- REVEL 0.15
- MetaLR 0.00
- MetaSVM -0.86
- CADD 2.72
- PolyPhen-2 0.00
- SIFT 0.19
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available