R27* (p.Arg27Ter) variant of HLA-DPA1 (P20036)
R27* (p.Arg27Ter) in HLA-DPA1 (P20036) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.44 / 1. The record also includes population frequency data and structural context.
R27* (p.Arg27Ter) variant details
- p.Arg27Ter
- rs1198838561
- TOPMed rs1198838561
- gnomAD rs1198838561
- NCI-TCGA Cosmic COSV6982
- Variant assessed as somatic; high impact.
- Stop Gained
- Variant Prioritization Score for Impact Estimate 0.441
- CADD 44.00
- UniProt: Variant assessed as somatic; high impact.
- Most common in the Non-Finnish European population (allele frequency 7.3e-05)
- Structural context available