R16S (p.Arg16Ser) variant of HLA-DPA1 (P20036)
R16S (p.Arg16Ser) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
R16S (p.Arg16Ser) variant details
- p.Arg16Ser
- gnomAD rs1437443220
- Missense
- Variant Prioritization Score for Impact Estimate 0.121
- REVEL 0.06
- MetaLR 0.00
- MetaSVM -0.90
- CADD 5.02
- PolyPhen-2 0.00
- SIFT 0.81
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available