Q88R (p.Gln88Arg) variant of HLA-DPA1 (P20036)
Q88R (p.Gln88Arg) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data, published literature, and structural context.
Q88R (p.Gln88Arg) variant details
- p.Gln88Arg
- gnomAD 6-33069724-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.327
- REVEL 0.16
- CADD 20.70
- PolyPhen-2 0.23
- SIFT 0.06
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available