Q88K (p.Gln88Lys) variant of HLA-DPA1 (P20036)
Q88K (p.Gln88Lys) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
Q88K (p.Gln88Lys) variant details
- p.Gln88Lys
- gnomAD 6-33069725-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.314
- REVEL 0.20
- CADD 23.40
- PolyPhen-2 0.70
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available