P49S (p.Pro49Ser) variant of HLA-DPA1 (P20036)
P49S (p.Pro49Ser) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
P49S (p.Pro49Ser) variant details
- p.Pro49Ser
- 1000Genomes rs2308907
- ESP rs2308907
- ExAC rs2308907
- TOPMed rs2308907
- Missense
- Variant Prioritization Score for Impact Estimate 0.215
- REVEL 0.12
- CADD 18.30
- PolyPhen-2 0.45
- SIFT 0.13
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available