N100S (p.Asn100Ser) variant of HLA-DPA1 (P20036)
N100S (p.Asn100Ser) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.21 / 1. The record also includes population frequency data, published literature, and structural context.
N100S (p.Asn100Ser) variant details
- p.Asn100Ser
- gnomAD 6-33069688-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.214
- REVEL 0.13
- CADD 21.90
- PolyPhen-2 0.24
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available