M7T (p.Met7Thr) variant of HLA-DPA1 (P20036)
M7T (p.Met7Thr) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
M7T (p.Met7Thr) variant details
- p.Met7Thr
- gnomAD rs1762391155
- Missense
- Variant Prioritization Score for Impact Estimate 0.219
- REVEL 0.08
- MetaLR 0.01
- MetaSVM -0.97
- CADD 15.80
- PolyPhen-2 0.11
- SIFT 0.38
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available