L24P (p.Leu24Pro) variant of HLA-DPA1 (P20036)
L24P (p.Leu24Pro) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
L24P (p.Leu24Pro) variant details
- p.Leu24Pro
- ExAC rs754558062
- TOPMed rs754558062
- gnomAD rs754558062
- Missense
- Variant Prioritization Score for Impact Estimate 0.379
- REVEL 0.26
- CADD 29.00
- PolyPhen-2 1.00
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available