K69E (p.Lys69Glu) variant of HLA-DPA1 (P20036)
K69E (p.Lys69Glu) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data, published literature, and structural context.
K69E (p.Lys69Glu) variant details
- p.Lys69Glu
- gnomAD 6-33069782-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.216
- REVEL 0.12
- CADD 20.30
- PolyPhen-2 0.11
- SIFT 0.04
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available