K33R (p.Lys33Arg) variant of HLA-DPA1 (P20036)
K33R (p.Lys33Arg) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.15 / 1. The record also includes population frequency data and structural context.
K33R (p.Lys33Arg) variant details
- p.Lys33Arg
- TOPMed rs1221207929
- gnomAD rs1221207929
- Missense
- Variant Prioritization Score for Impact Estimate 0.151
- REVEL 0.05
- CADD 20.40
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the Finnish in Finland (FIN) population (allele frequency 3.8e-05)
- Structural context available