I94V (p.Ile94Val) variant of HLA-DPA1 (P20036)
I94V (p.Ile94Val) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
I94V (p.Ile94Val) variant details
- p.Ile94Val
- gnomAD rs1325688041
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.07
- CADD 23.10
- PolyPhen-2 0.46
- SIFT 0.04
- Most common in the Latino/Admixed American population (allele frequency 6.7e-05)
- Structural context available