I32N (p.Ile32Asn) variant of HLA-DPA1 (P20036)
I32N (p.Ile32Asn) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
I32N (p.Ile32Asn) variant details
- p.Ile32Asn
- ExAC rs763185261
- gnomAD rs763185261
- Missense
- Variant Prioritization Score for Impact Estimate 0.3
- REVEL 0.13
- CADD 28.90
- PolyPhen-2 0.97
- SIFT 0.05
- Most common in the East Asian population (allele frequency 0.00019)
- Structural context available