H75R (p.His75Arg) variant of HLA-DPA1 (P20036)
H75R (p.His75Arg) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.09 / 1. The record also includes population frequency data and structural context.
H75R (p.His75Arg) variant details
- p.His75Arg
- TOPMed rs1435569420
- gnomAD rs1435569420
- Missense
- Variant Prioritization Score for Impact Estimate 0.0859
- REVEL 0.09
- CADD 0.27
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available