H75D (p.His75Asp) variant of HLA-DPA1 (P20036)
H75D (p.His75Asp) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
H75D (p.His75Asp) variant details
- p.His75Asp
- gnomAD rs1157374385
- Missense
- Variant Prioritization Score for Impact Estimate 0.235
- REVEL 0.18
- CADD 20.00
- SIFT 0.05
- Most common in the African/African-American population (allele frequency 2.4e-05)
- Structural context available