H36R (p.His36Arg) variant of HLA-DPA1 (P20036)
H36R (p.His36Arg) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
H36R (p.His36Arg) variant details
- p.His36Arg
- TOPMed rs1762190772
- Missense
- Variant Prioritization Score for Impact Estimate 0.242
- REVEL 0.15
- CADD 23.80
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available