H36Q (p.His36Gln) variant of HLA-DPA1 (P20036)
H36Q (p.His36Gln) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
H36Q (p.His36Gln) variant details
- p.His36Gln
- ExAC rs779490598
- TOPMed rs779490598
- gnomAD rs779490598
- Missense
- Variant Prioritization Score for Impact Estimate 0.175
- REVEL 0.17
- CADD 15.60
- PolyPhen-2 0.99
- SIFT 0.02
- Most common in the REMAINING population (allele frequency 6.7e-05)
- Structural context available