H36L (p.His36Leu) variant of HLA-DPA1 (P20036)
H36L (p.His36Leu) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data, published literature, and structural context.
H36L (p.His36Leu) variant details
- p.His36Leu
- gnomAD 6-33069880-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.252
- REVEL 0.16
- CADD 24.20
- PolyPhen-2 0.98
- SIFT 0.01
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available