G89C (p.Gly89Cys) variant of HLA-DPA1 (P20036)
G89C (p.Gly89Cys) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data, published literature, and structural context.
G89C (p.Gly89Cys) variant details
- p.Gly89Cys
- gnomAD 6-33069722-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.37
- REVEL 0.15
- CADD 22.80
- PolyPhen-2 0.93
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available