E86G (p.Glu86Gly) variant of HLA-DPA1 (P20036)
E86G (p.Glu86Gly) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data and structural context.
E86G (p.Glu86Gly) variant details
- p.Glu86Gly
- gnomAD rs1762169583
- Missense
- Variant Prioritization Score for Impact Estimate 0.241
- REVEL 0.14
- CADD 23.30
- PolyPhen-2 0.10
- SIFT 0.03
- Most common in the Latino/Admixed American population (allele frequency 6.5e-05)
- Structural context available