E78K (p.Glu78Lys) variant of HLA-DPA1 (P20036)
E78K (p.Glu78Lys) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
E78K (p.Glu78Lys) variant details
- p.Glu78Lys
- TOPMed rs1203697225
- gnomAD rs1203697225
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.11
- CADD 22.80
- PolyPhen-2 0.98
- SIFT 0.02
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available