E78D (p.Glu78Asp) variant of HLA-DPA1 (P20036)
E78D (p.Glu78Asp) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.18 / 1. The record also includes population frequency data and structural context.
E78D (p.Glu78Asp) variant details
- p.Glu78Asp
- ExAC rs749351610
- gnomAD rs749351610
- Missense
- Variant Prioritization Score for Impact Estimate 0.176
- REVEL 0.14
- CADD 14.20
- PolyPhen-2 0.14
- SIFT 0.13
- Most common in the Non-Finnish European population (allele frequency 1.5e-05)
- Structural context available