E52G (p.Glu52Gly) variant of HLA-DPA1 (P20036)
E52G (p.Glu52Gly) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
E52G (p.Glu52Gly) variant details
- p.Glu52Gly
- gnomAD 6-33069832-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.309
- REVEL 0.15
- CADD 26.30
- PolyPhen-2 0.99
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available