D66A (p.Asp66Ala) variant of HLA-DPA1 (P20036)
D66A (p.Asp66Ala) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
D66A (p.Asp66Ala) variant details
- p.Asp66Ala
- gnomAD rs1458170677
- Missense
- Variant Prioritization Score for Impact Estimate 0.328
- REVEL 0.21
- CADD 27.80
- PolyPhen-2 0.95
- SIFT 0.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available