A87S (p.Ala87Ser) variant of HLA-DPA1 (P20036)
A87S (p.Ala87Ser) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data and structural context.
A87S (p.Ala87Ser) variant details
- p.Ala87Ser
- 1000Genomes rs143602878
- ExAC rs143602878
- TOPMed rs143602878
- gnomAD rs143602878
- Missense
- Variant Prioritization Score for Impact Estimate 0.225
- REVEL 0.11
- CADD 15.80
- PolyPhen-2 0.98
- SIFT 0.09
- Most common in the 1KG:ESN population (allele frequency 0.0049)
- Structural context available