A82G (p.Ala82Gly) variant of HLA-DPA1 (P20036)
A82G (p.Ala82Gly) in HLA-DPA1 (P20036) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data, published literature, and structural context.
A82G (p.Ala82Gly) variant details
- p.Ala82Gly
- gnomAD 6-33069742-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.262
- REVEL 0.11
- CADD 15.80
- PolyPhen-2 0.07
- SIFT 0.04
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available
- Literature evidence available