T65A (p.Thr65Ala) variant of HCN4 (Q9Y3Q4)
T65A (p.Thr65Ala) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
T65A (p.Thr65Ala) variant details
- p.Thr65Ala
- Ensembl rs2043138008
- Missense
- Variant Prioritization Score for Impact Estimate 0.249
- REVEL 0.30
- MetaLR 0.58
- MetaSVM -0.16
- CADD 1.59
- PolyPhen-2 0.00
- SIFT 0.73
- Population evidence available
- Structural context available