S88R (p.Ser88Arg) variant of HCN4 (Q9Y3Q4)
S88R (p.Ser88Arg) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.37 / 1. The record also includes population frequency data and structural context.
S88R (p.Ser88Arg) variant details
- p.Ser88Arg
- TOPMed rs1265825959
- gnomAD rs1265825959
- Missense
- Variant Prioritization Score for Impact Estimate 0.369
- REVEL 0.28
- MetaLR 0.82
- MetaSVM 0.50
- CADD 22.00
- PolyPhen-2 0.04
- SIFT 0.01
- Population evidence available
- Structural context available