S67Y (p.Ser67Tyr) variant of HCN4 (Q9Y3Q4)
S67Y (p.Ser67Tyr) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.39 / 1. The record also includes population frequency data and structural context.
S67Y (p.Ser67Tyr) variant details
- p.Ser67Tyr
- Ensembl rs1595837618
- Missense
- Variant Prioritization Score for Impact Estimate 0.394
- REVEL 0.17
- MetaLR 0.76
- MetaSVM 0.31
- CADD 14.10
- PolyPhen-2 0.01
- SIFT 0.00
- Most common in the East Asian population (allele frequency 3.3e-05)
- Structural context available