R95L (p.Arg95Leu) variant of HCN4 (Q9Y3Q4)
R95L (p.Arg95Leu) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.56 / 1. The record also includes population frequency data and structural context.
R95L (p.Arg95Leu) variant details
- p.Arg95Leu
- gnomAD rs1321152002
- Missense
- Variant Prioritization Score for Impact Estimate 0.559
- REVEL 0.43
- MetaLR 0.89
- MetaSVM 0.83
- CADD 23.10
- PolyPhen-2 0.34
- SIFT 0.03
- Population evidence available
- Structural context available