R68Q (p.Arg68Gln) variant of HCN4 (Q9Y3Q4)
R68Q (p.Arg68Gln) in HCN4 (Q9Y3Q4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
R68Q (p.Arg68Gln) variant details
- p.Arg68Gln
- Ensembl rs1160213657
- Missense
- Variant Prioritization Score for Impact Estimate 0.381
- REVEL 0.23
- MetaLR 0.70
- MetaSVM -0.05
- CADD 15.90
- PolyPhen-2 0.08
- SIFT 0.59
- Most common in the Finnish in Finland (FIN) population (allele frequency 2.9e-05)
- Structural context available